KDEL antibody

Catalogue Number: ORB151336-BOR

Manufacturer:Biorbyt
Type:Polyclonal Primary Antibody - Conjugated
Alias:Lys Asp Glu Leu Antibody
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 200 ug
Host name: Rabbit
Clone:
Isotype:
Immunogen: KDEL containing peptide immunogen
Application: ICC, IF, WB, IHC

Additional Text

Concentration

1 mg/ml

Note

For research use only.

Antibody Clonality

Polyclonal

Storage Note

-20°C

Short Description

Rabbit polyclonal to KDEL (ATTO-594). The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER.