Catalogue Number: ORB257565-BOR
Manufacturer: | Biorbyt |
Molecular Weight: | 24.3 kDa |
Type: | Immunoglobulins |
Alias: | IgG1 |
Host Cell: | HEK293 cells |
Shipping Condition: | Blue Ice |
Unit(s): | 1 mg, 200 ug |
Application: | SDS-PAGE |
10 mg/mL
Untagged
For research use only.
-20°C
Tag FreeExperiment Notes: This protein carries no "tag". The protein has a calculated MW of 24.3 kDa. The protein migrates as 28-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.