Mouse IgG Fc protein

Catalogue Number: ORB257565-BOR

Manufacturer:Biorbyt
Molecular Weight:24.3 kDa
Type:Immunoglobulins
Alias:IgG1
Host Cell:HEK293 cells
Shipping Condition:Blue Ice
Unit(s): 1 mg, 200 ug
Application: SDS-PAGE

Additional Text

Concentration

10 mg/mL

Protein Tag

Untagged

Note

For research use only.

Storage Note

-20°C

Application Notes

Tag FreeExperiment Notes: This protein carries no "tag". The protein has a calculated MW of 24.3 kDa. The protein migrates as 28-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Short Description

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.