Protein L protein

Catalogue Number: ORB257805-BOR

Manufacturer:	Biorbyt
Type:	Other Proteins
Alias:	RPL, Protein L
Host Cell:	E.coli
Shipping Condition:	Blue Ice
Unit(s):	1 g, 10 mg, 2 mg
Application:	SDS-PAGE

Overview
Datasheets

Additional Text

Protein Tag

HIS Tag

Note

For research use only.

Application Notes

His TagExperiment Notes: Recombinant Protein L Protein is fused with the polyhistidine tag at N-terminus and a single cysteine at C-terminus. The reducing (R) protein migrates as a 36-38 kDa polypeptide .Protein L Protein can bind to VL-Kappa.

Storage Note

-20°C

Short Description

Protein L was isolated from the surface of bacterial species Peptostreptococcus magnus and was found to bind Ig(IgG,IgM,IgA,IgE and IgD) through L chain interaction, from which the name was suggested. Despite this wide-ranging binding capability with respect to Ig classes, Protein L is not a universal immunoglobilin-binding protein. Binding of Protein L to immunoglobulins is restricted to those containing kappa light chains (i.e., k chain of the VL domain). In humans and mice, kappa (k) light chains predominate. The remaining immunoglobulins have lambda (l) light chains. The recombinant protein contains four immunoglobulin (Ig) binding domains (Bdomains) of the native protein. Besides antibody, protein L is also suitable for binding of a wide range of antibody fragments such as Fabs, single-chain variable fragments (scFv), and domain antibodies (Dabs).

ORB257805 Datasheet

Price

£2,996.00

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