Catalogue Number: ORB259644-BOR
Manufacturer: | Biorbyt |
Type: | Polyclonal Primary Antibody - Unconjugated |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 200 ug |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | KLH conjugated synthetic peptide derived from human Osteocalcin. Please contact us for the exact immunogen sequence. The peptide is available as orb374879. |
Application: | ELISA, IHC-P, WB |
BGLAP
11 kDa
NP_954642.1
0.5 mg/ml
632
Rabbit polyclonal antibody to osteocalcin is the most abundant non-collagenous protein in bone, comprising almost 2% of total protein in the human body. It is important in bone metabolism and is used as a clinical marker for bone turnover, but its precise function remains elusive. With no known enzyme activity, osteocalcin's function depends on its structure. That structure has now been determined by X-ray crystallography, to reveal a negatively charged protein surface that places five calcium ions in positions complementary to those in hydroxyapatite, an important mineral component of bone. Using this recognition mechanism, osteocalcin could potentially modulate the crystal morphology and growth of hydroxyapatite. And in this complex, the carboxy terminus of osteocalcin, which promotes the adhesion of osteoblasts and osteoclasts in bone replacement, is readily accessible.
Affinity Purified
For research use only.
anti BGLAP antibody, anti BGP antibody, anti Bone gamma carboxyglutamate (gla) protein antibody, anti Bone gamma carboxyglutamate gla protein osteocalcin antibody, anti Bone gamma carboxyglutamate protein antibody, anti Bone gamma carboxyglutamate protein antibody, anti Bone Gla protein antibody, anti Gamma carboxyglutamic acid containing protein antibody, anti Gamma-carboxyglutamic acid-containing protein antibody, anti OC antibody, anti OCN antibody, anti OSTCN_HUMAN antibody, anti Osteocalcin antibody, anti OTTHUMP00000016586 antibody, anti PMF1 antibody
Polyclonal
Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.