SARS-ACSMS protein

Catalogue Number: ORB97847-BOR

Manufacturer:Biorbyt
Molecular Weight:37 kDa
Type:Virus Proteins
Shipping Condition:Blue Ice
Unit(s): 100 ug
Application: ELISA, WB

Additional Text

Note

For research use only.

Short Description

SARS-ACSMS(C) (residues 1051-1076, 1121-1154, 1162-1190) protein.SARS-ACSM contains the C-terminal t section of theSpike protein immunodominant fragments, amino acids:1051-1076, 1121-1154, 1162-1190.SARS-ACSM is purified by proprietary chromatographictechniques.The spike (S) glycoprotein of coronaviruses mediates viralentry into host cells.Spike (S)-glycoprotein of the virus interacts with a cellularreceptor and mediates membrane fusion to allow viralentry into susceptible target cells. It is a type 1 viralfusion protein that characteristically contains two heptadrepeat regions, denoted HR-N and HR-C, that formcoiled-coil structures within the ectodomain of the protein.Previous studies have shown that the two heptad repeatregions can undergo a conformational change from theirnative state to a 6-helix bundle (trimer of dimers), whichmediates fusion of viral and host cell membranes.

Storage Note

store at -20 °C avoid freeze/thaw cycles