Rabbit anti Human Protein Phosphatase 2 A/B delta

Catalogue Number: P160P-EXA

Manufacturer:	ExAlpha
Type:	Primary Antibody
Alias:	pp2A/Bd, rabbit anti protein phosphatase 2A, B subunit delta, PP2A B subunit delta
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Synthetic peptide conjugated to KLH derived from the N-terminus of PP2A/B delta
Application:	WB

Overview

Description

Description: PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, B , B and B . The B' (or B56) family consists of at least seven splice variants derived from five genes. RNA's for the two members of the B'' family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals. B is a novel isoform of the B class of PP2A regulatory subunits. It is widely expressed in rat tissues and appears to be involved in targeting PP2A to the cytosolic compartment.

Additional Text

Gene ID

5528

Gene Name

PPP2R5D

Uniprot ID

Q14738

Purification

Ammonium Sulfate Precipitated

Antibody Clonality

Polyclonal

Application Notes

Detects PP2A/B delta protein in rat testis by Western blot. Detects a 53 kDa band in rat brain, heart, lung, placenta, skeletal muscle, spleen, testis and thymus tissues lysates. Optimal concentration should be evaluated by serial dilutions. Applications: Western Blotting, Immunofluorescence

Storage Note

Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles

Price

£322.00

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