Papilloma Virus, Human, Type 18, E6 (hPV, Human Papillomavirus Type 18 E6, E6, Early Protein E6, HpV18gp1, Protein E6) (MaxLight 650)
Catalogue Number: P3105-23B-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 9L397 |
| Isotype: | IgG1, kappa |
| Immunogen: | Gel-purified HPV 18 E6-beta galactosidase fusion protein. |
| Application: | IP, WB, IHC |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumor suppressor proteins respectively. Can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies.
Additional Text
Specificity
Recognizes HPV 18 E6 and HPV 16 E6.
Purification
Protein A purified
Antibody Clonality
Monoclonal
P3105-23B-ML650 Datasheet
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