Papilloma Virus, Human, Type 18, E6 (hPV, Human Papillomavirus Type 18 E6, E6, Early Protein E6, HpV18gp1, Protein E6) (MaxLight 490)
Catalogue Number: P3105-23C-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 9L398 |
| Isotype: | IgG1, kappa |
| Immunogen: | Human Papilloma Virus, type 18, E6-beta galactosidase fusion protein. |
| Application: | WB, RIA, IHC, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumor suppressor proteins respectively. Can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies.
Additional Text
Specificity
Recognizes HPV 18 early protein (E6).
Purification
Protein A purified
Antibody Clonality
Monoclonal
P3105-23C-ML490 Datasheet
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