PCNA (Proliferating Cell Nuclear Antigen) (MaxLight 490)
Catalogue Number: P3115-12A-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3H2827 (PC10) |
| Isotype: | IgG2a |
| Immunogen: | Rat Proliferating Cell Nuclear Antigen-Protein A expression vector pR1T2T. |
| Application: | FC, IP, WB, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Proliferating cell nuclear antigen (PCNA), formerly known as cyclin, is a 36kD intranuclear acidic protein closely associated with proliferating cells. PCNA was originally identified in patients with systemic lupus erythematosus. It represents a component of DNA polymerase-b. The presence of PCNA is closely associated with the cell cycle. PCNA is expressed in high concentration in the late G1-phase before the DNA synthesis, and it reaches a maximum concentration in the S-phase. The level of PCNA declines during the G2 and M phases.
Additional Text
Specificity
Recognizes the human proliferating cell nuclear antigen (PCNA), a nuclear protein vital for cellular DNA synthesis. Species Crossreactivity: rat, vertebrates, insects, invertebrates, ferret, chicken, rabbit, Xenopus, mouse, equine, sheep, canine, feline, Cynomolgus monkey, Rhesus monkey amd hamster
Purification
Purified
Antibody Clonality
Monoclonal
P3115-12A-ML490 Datasheet
SUPPORT
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