PDCD1 (Programmed Cell Death 1, Programmed Cell Death Protein 1, CD279, HGNC:8760, hPD-1, PD1, PD-1, Protein PD-1, SLEB2) (MaxLight 490)
Catalogue Number: P3120-61L1-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | RMP1-30 |
| Isotype: | IgG2b |
| Immunogen: | PD-1 transferred BHK cells. |
| Application: | FC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD279 is a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279.
Additional Text
Specificity
Recognizes mouse CD279. Does not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.
Purification
Protein G purified
Antibody Clonality
Monoclonal
P3120-61L1-ML490 Datasheet
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