Perforin
Catalogue Number: P3340-05-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | dG9 |
| Isotype: | IgG2b, kappa |
| Immunogen: | Purified granules from human YT lymphoma cell line |
| Application: | FC, ICC, IP, IHC |
Description
Description: Perforin is a 70kD cytolytic protein with structural and functional similarities to complement component 9 (C9). It is stored in cytoplasmic granules of cytotoxic T cells and NK cells and after its release it forms transmembrane pores in the target cells to kill it. As perforin is a key effector molecule for cell-mediated cytolysis, defects of its gene can cause severe disorders.
Additional Text
Gene Name
PRF1
Uniprot ID
P14222
Gene ID
5551
Purification
Protein A purified
Antibody Clonality
Monoclonal
P3340-05 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations