Recombinant Human KDR Protein( Fc Tag)

Catalogue Number: PDMH100192-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Protein Kinases
Host Cell:Mammalian Cells
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug

Description

Description: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Additional Text

Gene Name

KDR

Gene ID

3791

Uniprot ID

P35968

Protein Tag

Fc Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Specificity

CD309;CD309 antigen;EC 2.7.10.1;Fetal liver kinase 1;FLK-1;FLK1;FLK1;mouse;homolog of;Kdr;Kinase insert domain receptor (a type III receptor tyrosine kinase);Kinase insert domain receptor;KRD1;Ly73;Protein tyrosine kinase receptor FLK1;Protein-tyrosine kinase receptor flk-1;soluble VEGFR2;Tyrosine kinase growth factor receptor;Vascular endothelial growth factor receptor 2;VEGFR 2;VEGFR;VEGFR-2;VEGFR2;VGFR2