Recombinant Human PSAP Protein(His Tag)

Catalogue Number: PDMH100202-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Type:	Other Recombinant Protein
Host Cell:	Mammalian Cells
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug

Overview
Datasheets

Description

Description: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Additional Text

Gene Name

PSAP

Gene ID

5660

Uniprot ID

P07602

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Specificity

A1 activator;Cerebroside sulfate activator;Co-beta-glucosidase;Component C;CSAct;Dispersin;GLBA;Glucosylceramidase activator;Proactivator polypeptide;Proactivator polypeptide precursor;Prosaposin (sphingolipid activator protein 1);prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy);Prosaposin;Protein A;Protein C;PSAP;SAP-1;SAP-2;SAP;SAP1;Saposin A;Saposin B;Saposin B Val;Saposin C;Saposin D;Saposin-D;Saposins;Sgp1;Sphingolipid activator protein 1;Sphingolipid activator protein 2;Sulfated glycoprotein 1;Sulfatide/GM1 activator

PDMH100202 Protocol

PDMH100202 MSDS

Price

£415.00

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