Recombinant Human IL5 Protein(His Tag)

Catalogue Number: PDMH100203-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Interleukins
Alias:B-cell differentiation factor I;Colony stimulating factor;EDF;Eosinophil differentiation factor;IL-5;IL5;IL5;Interleukin 5 (colony stimulating factor;eosinophil);Interleukin 5;Interleukin-5;T Cell Replacing Factor;T-cell replacing factor;TRF
Host Cell:Mammalian Cells
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug

Description

Description: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with an the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 with anin a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

Additional Text

Gene ID

3567

Gene Name

IL5

Uniprot ID

P05113

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.