Recombinant Human TLR2 Protein(His Tag)

Catalogue Number: PDMH100206-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Other Recombinant Protein
Host Cell:Mammalian Cells
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug

Description

Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Additional Text

Gene Name

TLR2

Gene ID

7097

Uniprot ID

O60603

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Specificity

CD282;CD282 antigen;TIL 4;TIL4;TLR 2;TLR2;TLR2;Toll like receptor 2;Toll like receptor 2 precursor;Toll-like receptor 2;Toll/interleukin 1 receptor like 4;Toll/interleukin 1 receptor like protein 4;Toll/interleukin receptor like protein 4;Toll/interleukin-1 receptor-like protein 4