Recombinant Human F9 Protein(His Tag)

Catalogue Number: PDMH100254-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Type:	Other Recombinant Protein
Host Cell:	stable cell line
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug

Overview
Datasheets

Description

Description: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with an Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

Additional Text

Gene ID

2158

Gene Name

Uniprot ID

P00740

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Specificity

Christmas Disease;Christmas factor;Coagulant factor IX;Coagulation factor 9;Coagulation factor IX;Coagulation factor IXa heavy chain;F9;FA9;Factor 9;Factor IX Deficiency;FactorIX;FIX;Haemophilia B;HEMB;MGC129641;MGC129642;P19;Plasma Thromboplastic Component;Plasma thromboplastin component;PTC

PDMH100254 Protocol

PDMH100254 MSDS

Price

£415.00

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