TGFβ1 Inhibitor (TGFβ1 Binding Peptide)
Catalogue Number: PG-002-PEP
PG-002 Image 1
PG-002 Image 1
Equivalent Inhibitory Activity to TGFβ-Neutralizing Antibody The inhibitory activity against TGFβ1 was measured by SBE Reporter Assay, and PG-002 showed 100% inhibitory activity at 10nM against 0.13nM TGFβ1 (right figure). Using the panel assay, we also confirmed that it does not inhibit other signaling pathways.
| Manufacturer: | Peptigrowth |
| Molecular Weight: | 2587.90 (Acetate) |
| Type: | Peptide |
| Shipping Condition: | Dry Ice |
| Unit(s): | 10 ug, 100 ug |
| Application: | Cell culture |
Description
Description:
PeptiGrowth succeeded in developing a synthetic peptide that functions as TGFβ1 inhibitor. Existing small molecule inhibitors must enter the cells to inhibit TGFβ1 activity, while Catalog # PG-002 binds to TGFβ1 extracellularly. Use of Catalog # PG-002 is recommended when neutralization of TGFβ1 is required in cell culture. Please note that 10 ug of Catalog # PG-002 is equivalent to ~600 ug of antibody 1D11 due to difference in molecular weight.
Since it is produced by complete chemical synthesis, we are able to provide animal-free certification.
Additional Text
PG-001 Biological Activity
Binds to TGFβ1 extracellularly and inhibits its activity
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