Human PKC iota Protein (PKC-HB101)
Catalogue Number: PKC-HB101-KAT
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 68.78 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result. |
| Physical state: | Liquid |
| Type: | Protein Kinases |
| Alias: | nPKC-iota; PRKCI; DXS1179E |
| Host Cell: | Baculovirus-Insect Cells(Sf9) |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
| Application: | WB |
Description
Description: PKClambda/iota belongs to the third group of the PKC family, atypical PKC (aPKC), together with PKCzeta based on its sequence divergence from conventional and novel PKCs observed not only in the N-terminal regulatory domain but also in the kinase domain. Although one of the most distinct features of aPKC is its single, unrepeated cysteine-rich domain, recent studies have revealed that the N-terminal regulatory domain has additional aPKC-specific structural motifs involved in various protein-protein interactions, which are important for the regulation and the subcellular targeting of aPKC.
Additional Text
Gene Name
PRKCI
Uniprot ID
P41743
Gene ID
5584
Protein Tag
HIS Tag
Storage Note
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin
Less than 1 EU per µg by the LAL method.
Short Description
Recombinant Human PKC iota Protein is expressed from Baculovirus-Insect Cells(Sf9) with His tag at the C-terminus.It contains Met10-Val596.
PKC-HB101 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations