Recombinant Human IL-16 (129 a.a.) protein(N-His)

Catalogue Number: PKSH034104-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Interleukins
Alias:LCF (Lymphocyte Chemoattractant Factor)|NIL;Interleukin;IL16;LCF;NIL16;PRIL16;prIL-16;IL-16;Interleukin-16;LCF (Lymphocyte Chemoattractant Factor);Lymphocyte chemoattractant factor;Pro-Interleukin-16
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug

Description

Description: Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.

Additional Text

Gene ID

3603

Uniprot ID

Q14005

Gene Name

IL16

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.