Recombinant Human IL-19 protein(His Tag)
Catalogue Number: PKSH034106-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Interleukins |
| Alias: | MDA;ZMDA;NG.1;IL 10C;IL 19;IL-10C;IL-19;Interleukin 19;Interleukin-19;MDA1;Melanoma differentiation-associated protein-like protein;IL19;ZMDA1|Melanoma differentiation-associated protein-like protein |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Application: | Cell culture |
Description
Description: The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the epithelial barrier with dextran sodium sulfate leads to increased IL-19 expression. Attenuated colitis in IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. Microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease.
Additional Text
Gene ID
29949
Gene Name
IL19
Uniprot ID
Q9UHD0
Protein Tag
HIS Tag
Storage Note
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
PKSH034106 Protocol
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