Recombinant Human IL-24 protein(His Tag)

Catalogue Number: PKSH034109-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Type:	Interleukins
Host Cell:	E.coli
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Application:	Cell culture

Overview
Datasheets

Description

Description: Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I intereferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal. In addition, acts as a quality control mechanism for the ubiquitin proteasome system by alerting the cell to proteasome dysfunction through activation of PKR/EIF2AK2.

Additional Text

Uniprot ID

Q13007

Gene ID

11009

Gene Name

IL24

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Specificity

MDA-7 (Melanoma Differentiation-Associated gene 7 protein)|MDA;MOB;Melanoma Differentiation Association Protein;IL24;C49A;FISP;IL10B;MDA7;MOB5;ST16;MDA-7 (Melanoma Differentiation-Associated gene 7 protein);Melanoma Differentiation Association Protein 7;IL 24;IL 4 induced secreted protein;IL-24;interleukin 24;Interleukin-24;MDA-7;Melanocyte associated Mda 7;Melanoma differentiation-associated gene 7 protein;Suppression of tumorigenicity 16;Suppression of tumorigenicity 16 (melanoma differentiation);Suppression of tumorigenicity 16 protein

PKSH034109 Protocol

PKSH034109 MSDS

Price

£442.00

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Quantity
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