Recombinant Human TWEAK protein(His Tag)
Catalogue Number: PKSH034128-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Cytokines |
| Alias: | Apo3 Ligand;DR3LG;TNFSF12|TNFSF12;DR3LG;Apo3 Ligand |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Application: | Cell culture |
Description
Description: TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. It can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found that TNFSF12 promotes proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. TNFSF12 also is a weak inducer of apoptosis in some cell types and mediates NF-kappa-B activation.
Additional Text
Uniprot ID
O43508
Protein Tag
HIS Tag
Gene ID
407977; 8742
Gene Name
TNFSF12, TNFSF12-TNFSF13
Storage Note
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
PKSH034128 Protocol
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