Recombinant Human HMGB1 protein(His Tag)

Catalogue Number: PKSH034144-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:DNA Binding Proteins
Alias:HMG-1;HMG1;HMG3;SBP-1
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Application: Cell culture

Description

Description: High mobility group protein B1 is a member of the HMGB family consisting of three members; HMGB1; HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein; HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile; it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte; T cell; dendritic cell activities in inflammatory responses.

Additional Text

Gene ID

3146

Gene Name

HMGB1

Uniprot ID

P09429

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.