Recombinant Human Activin B protein(His Tag)

Catalogue Number: PKSH034166-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Type:	Growth Factors
Alias:	Activin Beta B;INHBB;inhibin beta B chain
Host Cell:	E.coli
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Application:	Cell culture

Overview
Datasheets

Description

Description: Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in many cell types and organs, such as gonads, pituitary gland, and placenta. In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization. It participates in androgen synthesis enhancing LH action in the ovary and testis. In the male, activin enhances spermatogenesis. Also, Activin plays a role in wound repair and skin morphogenesis. Activin is strongly expressed in wounded skin, and overexpression of activin in the epidermis of transgenic mice improves wound healing and enhances scar formation. Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and kidney. There is also evidence showed that lack of activin during development results in neural developmental defects.

Additional Text

Gene Name

INHBB

Gene ID

3625

Uniprot ID

P09529

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

PKSH034166 Protocol

PKSH034166 MSDS

Price

£442.00

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