Recombinant Human CCL4 protein(His Tag)
Catalogue Number: PKSH034170-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Cytokines |
| Alias: | ACT-2;MIP-1b: Macrophage Inflammatory Protein-1β|MIP-1b: Macrophage Inflammatory Protein-1β;ACT-2 |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Application: | Cell culture |
Description
Description: CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. The inflammatory chemokine (C-C motif) ligand 4 (CCL4) plays an important role in the pathogenesis and progression of cancer. In particular, higher serum CCL4 levels in patients with oral squamous cell carcinoma (OSCC) are associated with a more advanced stage of disease. CCL4 may be a new molecular therapeutic target for inhibition of lymphangiogenesis and metastasis in OSCC. CCL3 and CCL4 loci may be marker SNPs for risk of HCV treatment outcome. CCL4 can enhance the recruitment of preosteoclasts to bone in the early stage, and the reduction of CCR5 promotes osteoclastogenesis when RANKL is prevalent.
Additional Text
Uniprot ID
P13236
Gene ID
388372; 6351
Protein Tag
Untagged
Gene Name
CCL4, CCL4L1
Storage Note
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
PKSH034170 Protocol
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