Recombinant Human IL-12 p40 protein(His Tag)

Catalogue Number: PKSH034191-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Interleukins
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Application: Cell culture

Description

Description: Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

Additional Text

Uniprot ID

P29460

Gene Name

IL12B

Gene ID

3593

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Specificity

IL-12/IL-23 p;IL-12 subunit p;NK cell stimulatory factor chain;NK cell Stimulating Factor Chain;CLMF p;IMD;IL12B;CLMF;CLMF2;IL-12B;IMD28;IMD29;NKSF;NKSF2;Cytotoxic lymphocyte maturation factor 40 kDa subunit;Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40);IL-12/IL-23 p40;NK cell Stimulating Factor Chain 2;p40;Interleukin-12 subunit beta;CLMF p40;IL-12 subunit p40;NK cell stimulatory factor chain 2;IL 12B;IL12 p40;Interleukin 12 beta chain;Interleukin 12 p40|Interleukin-12 subunit beta;IL-12 subunit p40;IL-12B;Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40);NK cell Stimulating Factor Chain 2