Recombinant Mouse CXCL1 protein(His Tag)

Catalogue Number: PKSM041463-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Growth Factors
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Application: Cell culture

Description

Description: Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Mouse KC shows approximately 63% identity to that of mouse MIP-2. KC is also approximately 60% identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the orthologs of the human GROs and rat CINCs. Cxcl1 has chemotactic activity for neutrophils, and contributes to neutrophil activation during inflammation. Hematoregulatory chemokine, in vitro, suppresses hematopoietic progenitor cell proliferation.

Additional Text

Gene Name

CXCL1

Gene ID

14825

Uniprot ID

P12850

Protein Tag

Untagged

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Specificity

C-X-C Motif Chemokine 1;CXCL1;GRO;GRO-Alpha(1-73);GRO1;GROA;Growth-Regulated Alpha Protein;MGSA;Melanoma Growth Stimulatory Activity;NAP-3;Neutrophil-Activating Protein 3;SCYB1|Growth-Regulated Alpha Protein;C-X-C Motif Chemokine 1;GRO-Alpha(1-73);Melanoma Growth Stimulatory Activity;MGSA;Neutrophil-Activating Protein 3;NAP-3;CXCL1;GRO;GRO1;GROA;MGSA;SCYB1