Recombinant Mouse IL-24 protein(His Tag)
Catalogue Number: PKSM041470-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Interleukins |
| Alias: | MCGF (Mast Cell Growth Factor);Multi-CSF;HCGF;P-cell stimulation factor;Interleukin-3b|Mda;HCGF;Interleukin-3b;MCGF (Mast Cell Growth Factor);Multi-CSF;P-cell stimulation factor;Mda7;Il24;Il24;Il24 |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Application: | Cell culture |
Description
Description: Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I intereferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal. In addition, acts as a quality control mechanism for the ubiquitin proteasome system by alerting the cell to proteasome dysfunction through activation of PKR/EIF2AK2.
Additional Text
Gene Name
IL24
UniProt ID
Q925S4
Protein Tag
HIS Tag
Storage Note
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Gene ID
93672
PKSM041470 Protocol
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