Recombinant Mouse IL-28B protein(His Tag)

Catalogue Number: PKSM041474-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Interleukins
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Application: Cell culture

Description

Description: Interleukin-28B; also known as Cytokine Zcyto22; Interferon lambda-3; Interferon lambda-4; IFNL3; IFNL4; ZCYTO22 and IL28B; is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition; IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Additional Text

Gene Name

IFNL3

Uniprot ID

Q8CGK6

Gene ID

338374

Protein Tag

HIS Tag

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Specificity

Cytokine Zcyto;IL-12 subunit p;ZCYTO;Cytokine Zcyto22;Cytotoxic Lymphocyte Maturation Factor 35 kDa;IFNL4;IFN-Lambda-3;IFN-Lambda-4;IL-12 subunit p35;IL-12A;IL-28B;IL28C;IL-28C;Interferon Lambda-3;Interferon Lambda-4;Interleukin-12 subunit alpha;Interleukin-28B;Interleukin-28C;ZCYTO22;Il28;Il28b;Ifnl3|Interleukin-12 subunit alpha;IL-12 subunit p35;IL-12A;Cytotoxic Lymphocyte Maturation Factor 35 kDa