Recombinant Mouse IL-36 gamma protein(His Tag)

Catalogue Number: PKSM041481-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Interleukins
Alias:IL-17E|Il1f;IL-1-related protein;Interleukin-1 homolog;IL-1F;IL-1H;IL-1RP;IL-1 epsilon;IL-1F9;IL-1H1;IL-1-related protein 2;IL-1RP2;Interleukin-1 homolog 1;Interleukin-36 gamma;Il1f9;Il36g;IL-17E
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Application: Cell culture

Description

Description: Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.

Additional Text

Protein Tag

HIS Tag

Uniprot ID

Q8R460

Storage Note

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.