Recombinant 2019-nCoV Envelope Protein (His Tag)

Catalogue Number: PKSR030488-ELA

Manufacturer:Elabscience
Shelf Life:6 months
Type:Fusion Protein
Alias:2019-nCoV E protein; 2019-nCoV sM protein
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 1 mg

Description

Description: Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.

Additional Text

Protein Tag

6xHIS Tag

Description

Recombinant 2019-nCoV Envelope Protein is produced by our E.coli expression system and the target gene encoding Met1-Val75 is expressed with a BBP, 6His tag at the N-terminus.