Recombinant Human ACE2 Protein (mFc Tag)

Catalogue Number: PKSR030494-ELA

Manufacturer:Elabscience
Shelf Life:6 months
Type:Proteases
Alias:Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH; Metalloprotease MPROT15; ACE2
Shipping Condition:Blue Ice
Unit(s): 10 ug, 50 ug

Description

Description: Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

Additional Text

Uniprot ID

Q9BYF1

Protein Tag

mFC Tag

Description

Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a mFc tag at the C-terminus.

Price
120.00


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