Human PLAU/uPA Protein (pro form) (PLA-HM102)
Catalogue Number: PLA-HM102-KAT
PLA-HM102 Image
PLA-HM102 Image
PLA-HM102 Image
PLA-HM102 Image
The purity of Human PLAU (pro form) is greater than 95% as determined by SEC-HPLC.
PLA-HM102 Image
Human PLAU (pro form) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
PLA-HM102 Image
Immobilized Human PLAU, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human uPAR, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 47.5 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Proteases |
| Alias: | PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Additional Text
Protein Tag
HIS Tag
Short Description
Recombinant Human PLAU/uPA Protein (pro form) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser21-Leu431.
UniProt ID
P00749-1
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Human PLAU, His Tag at 0.5Oeg/ml (100Oel/Well) on the plate. Dose response curve for Human uPAR, hFc Tag with the EC50 of 11.9ng/ml determined by ELISA. See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
PLA-HM102 Datasheet
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