HAV-VP4-VP2 (residues 55-164), Hepatitis A Virus Capsid Proteins VP4-VP2, recombinant, E. coli

Catalogue Number: PR-1120-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Molecular Weight:44 kDa
Physical state:Liquid
Type:Virus Proteins
Shipping Condition:Blue Ice
Unit(s): 100 ug
Application: ELISA, WB

Description

Description: The protein contains the HAV structural proteins VP2-VP4 immunodominant regions. Hepatitis A Virus VP2-VP4 protein is purified by proprietary chromatographic techniques. Background: HAV, the prototype of the genus Hepatovirus, belongs to the family Picornaviridae. Its 7.5-kb single-stranded RNA genome bears different distinct regions: the 5' and 3' noncoding regions (NCR), the P1 region, which encodes the structural proteins VP1, VP2, VP3, and a putative VP4, and the P2 and P3 regions encoding nonstructural proteins associated with replication. Hepatitis A virus (HAV) encodes a single polyprotein which is posttranslationally processed into the functional structural and nonstructural proteins. Only one protease, viral protease 3C, has been implicated in the nine protein scissions.

Additional Text

Additional Information

Specificity: Immunoreactive with sera of HAV-infected individuals.

Application Notes

Recombinant HAV-VP4-VP2 may be used in ELISA and Western blots, excellent for detection of HAV with minimal specificity problems.

Storage Note

store at -20 °C|12 months|avoid freeze/thaw cycles