Catalogue Number: PR-1120-JEN
| Manufacturer: | Jena Bioscience |
| Shelf Life: | 12 months |
| Molecular Weight: | 44 kDa |
| Physical state: | Liquid |
| Type: | Virus Proteins |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Application: | ELISA, WB |
Description: The protein contains the HAV structural proteins VP2-VP4 immunodominant regions. Hepatitis A Virus VP2-VP4 protein is purified by proprietary chromatographic techniques. Background: HAV, the prototype of the genus Hepatovirus, belongs to the family Picornaviridae. Its 7.5-kb single-stranded RNA genome bears different distinct regions: the 5' and 3' noncoding regions (NCR), the P1 region, which encodes the structural proteins VP1, VP2, VP3, and a putative VP4, and the P2 and P3 regions encoding nonstructural proteins associated with replication. Hepatitis A virus (HAV) encodes a single polyprotein which is posttranslationally processed into the functional structural and nonstructural proteins. Only one protease, viral protease 3C, has been implicated in the nine protein scissions.
Specificity: Immunoreactive with sera of HAV-infected individuals.
Recombinant HAV-VP4-VP2 may be used in ELISA and Western blots, excellent for detection of HAV with minimal specificity problems.
store at -20 °C|12 months|avoid freeze/thaw cycles