HIV-1 p17/p24, Human Immunodeficiency Virus 1 Antigens, recombinant, E. coli

Catalogue Number: PR-1207-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Physical state:Liquid
Type:Virus Proteins
Shipping Condition:Blue Ice
Unit(s): 100 ug
Application: ELISA, WB

Description

Description: The protein contains the full-length sequence of HIV-1 core proteins: Core protein p17 (matrix protein), and Core protein p24 (major capsid protein). The fusion protein was purified by proprietary chromatographic technique. Background: HIV belongs to the retrovirus family, distinguished by possession of a viral reverse transcriptase that transcribes viral RNA into DNA which is integrated into the host-cell genome. The outer envelope is acquired during virion budding and is studded with spikes formed by the two major viral-envelope glycoproteins (the surface protein gp120 and the transmembrane protein gp41). The central core contains four viral proteins (p24 - the major capsid protein, p17 - a matrix protein, p9, and p7), two copies of the HIV RNA genome (to which p7 and p9 are bound), and three viral enzymes (reverse transcriptase, integrase, and protease) essential for viral replication.

Additional Text

Additional Information

Specificity: Immuno reactive with all sera of HIV-I infected individuals.

Application Notes

May be used in ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.

Storage Note

store at -20 °C|12 months|avoid freeze/thaw cycles