HIV-type O Envelope, Human Immunodeficiency Virus Type O Antigen, recombinant, E. coli

Catalogue Number: PR-1209-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Physical state:Liquid
Type:Virus Proteins
Shipping Condition:Blue Ice
Unit(s): 100 ug
Application: ELISA, WB

Description

Description: Recombinant HIV type-O peptide, containing the HIV type-O transmembrane envelopederived specific sequence. Detects all clades of HIV type-O infected individuals responding to HIV type-O envelope proteins. The protein was purified by proprietary chromatographic technique. Background: HIV belongs to the retrovirus family, distinguished by possession of a viral reverse transcriptase that transcribes viral RNA into DNA which is integrated into the host-cell genome. Based on genetic variability in the envelope (env) gene, HIV-1 can be subdivided into at least 10 distinct subtypes (designated A to J) responsible for separate geographic pandemics. Phylogenetic analyses have shown that each subtype in this major group (group M) is approximately equidistant from the others, as if arising from a common ancestor. In contrast, a few divergent HIV-1 strains form a cluster distinct from group M and have been categorized as members of the outlier group (group O).

Additional Text

Additional Information

Specificity: Immuno reactive with all sera of HIV type-O infected individuals.

Application Notes

May be used in ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.

Storage Note

store at 4 °C|12 months|Please do NOT freeze