Catalogue Number: PR-1229-JEN
| Manufacturer: | Jena Bioscience |
| Shelf Life: | 12 months |
| Physical state: | Liquid |
| Type: | Virus Proteins |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Application: | ELISA, WB |
Description: The protein contains the Rubella Virus glycoprotein E2 immunodominant regions, amino acids 31-105. The protein is purified by proprietary chromatographic technique. Background: Rubella virus is an enveloped positivestrand RNA virus of the family TOGAVIRIDAE. The genome encodes two open reading frames (ORFs): the 5'-proximal ORF encodes viral nonstructural proteins (NSP) that are responsible for viral genome replication, while the 3'-proximal ORF encodes three virion structural proteins (SP), the capsid protein (CP), and the two envelope glycoproteins, E2 and E1. During virus assembly, the capsid interacts with genomic RNA to form nucleocapsids. The rubella virus (RV) structural proteins: capsid, E2, and E1 are synthesized as a polyprotein precursor. The signal peptide that initiates translocation of E2 into the lumen of the endoplasmic reticulum remains attached to the carboxy terminus of the capsid protein after cleavage by signal peptidase.
Specificity: Immunoreactive with sera of Rubella virus-infected individuals.
Antigen in ELISA and Western blots, excellent antigen for detection of Rubella virus with minimal specificity problems.
store at -20 °C|12 months|avoid freeze/thaw cycles