Rab5A, Ras-associated, small GTP-binding protein, rat, recombinant, E. coli

Catalogue Number: PR-184-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Molecular Weight:24 kDa
Physical state:Liquid
Type:Other Enzymes
Shipping Condition:Dry Ice
Unit(s): 50 ug

Description

Description: Rab5A is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The small Rab5A GTPase is localized to plasma membrane, clathrin coated vesicles, caveosomes and early endosomes. Rab5 is a key regulator of the early endocytic pathway and plays a role in early endosome fusion and caveolar vesicle targeting to early endosomes. Furtermore it is also implicated in EGF receptor activation and apoptotic cell engulfment.

Additional Text

Accession Number

NP_073183