H-Ras ΔC (S17N), Harvey rat sarcoma viral oncogene homolog, residues 1-166, human, recombinant, E. coli
Catalogue Number: PR-202-JEN
| Manufacturer: | Jena Bioscience |
| Shelf Life: | 12 months |
| Molecular Weight: | 19.5 kDa (171 amino acids) |
| Physical state: | Liquid |
| Type: | Other Enzymes |
| Shipping Condition: | Dry Ice |
| Unit(s): | 50 ug |
Description
Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). H-Ras ΔC (aa 1 - 171) lacks the C-terminus with the CaaX recognition sequence necessary for anchoring Ras into the plasma membrane. The mutation S17N results in a 40-fold increase in the affinity for GTP without affecting its affinity for GDP. Protein preparation is 95% GDP- and 5% GTP-loaded, measured by HPLC.
Additional Text
Accession Number
NP_005334
PR-202 MSDS
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