H-Ras (Q61L), Harvey rat sarcoma viral oncogene homolog, human, recombinant, E. coli

Catalogue Number: PR-203-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Molecular Weight:21.3 kDa (189 amino acids)
Physical state:Liquid
Type:Other Enzymes
Shipping Condition:Dry Ice
Unit(s): 50 ug

Description

Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). The mutation Q61L results in a decreased GTPase activity as well as increased GDP/GTP exchange. This mutant constitutively activates the Ras-signaling pathway. Protein preparation is 77% GDP- and 23% GTP-loaded, measured by HPLC.

Additional Text

Accession Number

NP_005334