Ran - E70A, Ras-related nuclear protein, TC4, human, recombinant, E. coli

Catalogue Number: PR-215-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Molecular Weight:24.0 kDa (216 amino acids)
Physical state:Liquid
Type:Other Enzymes
Shipping Condition:Dry Ice
Unit(s): 50 ug

Description

Description: Ran (Ras-related nuclear protein, TC4) belongs to the Ras superfamily of GTP binding proteins. It acts in cellular processes such as nuclear transport, mitotic spindle assembly, and post-mitotic nuclear assembly. The mutation E70A results in inhibition of the guanine exchange reaction mediated by RCC1, the guanine nucleotide exchange factor (GEF) for Ran. Protein preparation is 85% GDP-loaded, measured by HPLC.

Additional Text

Accession Number

NM_006325