KRasHis - G-domain, Kirsten rat sarcoma viral oncogene homolog, G-domain, human, recombinant, E. coli

Catalogue Number: PR-239-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Molecular Weight:25 kDa
Physical state:Liquid
Type:Other Enzymes
Shipping Condition:Blue Ice
Unit(s): 50 ug

Description

Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signalling and transport pathways. KRAS gene performs an essential function in normal tissue signaling, and the mutation of a KRAS gene is an essential step in the development of many cancers. KRAS is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. Protein preparation is 100 % GDP-loaded, measured by HPLC. Human K-Ras is a truncated protein containing amino acids 1-163. The 6His-tag is located at the N-terminus.

Additional Text

Protein Tag

HIS Tag

Accession Number

NM_004985.3