Rap1B ΔC, Ras-proximate 1B, deletion of 17 C-terminal residues, human, recombinant, E. coli
Catalogue Number: PR-301-JEN
| Manufacturer: | Jena Bioscience |
| Shelf Life: | 12 months |
| Molecular Weight: | 19.0 kDa (167 amino acids) |
| Physical state: | Liquid |
| Type: | Other Enzymes |
| Shipping Condition: | Dry Ice |
| Unit(s): | 50 ug |
Description
Description: Rap (Ras-proximate) proteins are GTPases that belong to the Ras superfamily of small GTP binding proteins. Rap1B is known to antagonize the mitotic and transforming activity of Ras. Rap1B can be activated by cAMP known to either stimulate or inhibit cell proliferation. The deletion of 17 C-terminal amino acids in Rap1B ΔC leads to the loss of the phosphorylation site Ser179 and the geranyl-geranylation site. Protein preparation is 53% GDP- and 47% GTP-loaded, measured by HPLC.
Additional Text
Accession Number
NM_015646
PR-301 MSDS
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