RCC1 (RanGEF), Regulator of Chromosome Condensation, Ran Guanine Exchange Factor, human, recombinant, E. coli
Catalogue Number: PR-306-JEN
| Manufacturer: | Jena Bioscience |
| Shelf Life: | 12 months |
| Molecular Weight: | 44.97 kDa (421 amino acids) |
| Physical state: | Liquid |
| Type: | Other Recombinant Protein |
| Shipping Condition: | Dry Ice |
| Unit(s): | 50 ug |
Description
Description: RCC1 (Regulator of Chromosome Condensation, a β propeller chromatin-bound protein) catalyzes guanine nucleotide exchange of the Ras-related nuclear protein Ran. RCC1 is the guanine nucleotide exchange factor (GEF) for Ran which induces exchange between the bound GDP and cellular GTP. Genetic studies have suggested that RCC1 may be involved in sensing the replication state of DNA and controlling the activation of Cdc2/cyclin B protein kinase through Ran.
Additional Text
Accession Number
BC010067
PR-306 MSDS
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