RafRBDGST (C-Raf), Ras Binding Domain of Raf, C-Raf 1 Kinase, human, recombinant, E. coli
Catalogue Number: PR-366-JEN
| Manufacturer: | Jena Bioscience |
| Shelf Life: | 12 months |
| Molecular Weight: | 42 kDa |
| Physical state: | Liquid |
| Type: | Protein Kinases |
| Shipping Condition: | Dry Ice |
| Unit(s): | 300 ug |
Description
Description: Raf is a member of the serine/threonine proteine kinase family involved in regulation of cell growth and differentiation and is the most important effector of Ras. Full-length Raf is composed of three conserved regions responsible for interaction with Ras, for phosphorylation and for catalytic activity. RafRBD (Ras binding domain, amino acids 50-132) mediates interaction with membrane-anchored Ras necessary for activation of the kinase activity of Raf. The GST-Tag facilitates the protein`s application in typical GST pull-down assays. The protein is GST-tagged on its N-terminus. There is a 7 AA linker between GST and RBD.
Additional Text
Gene ID
5894
Gene Name
RAF1
Uniprot ID
P04049
Protein Tag
GST Tag
Accession Number
X03484
Additional Information
Reommended thawing and freezing : Thaw the protein quickly at approx. 30 °C in a water bath and refreeze aliquots fast on dry ice.
PR-366 MSDS
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