Human IL-6 protein
Catalogue Number: PRP1012-ABK
| Manufacturer: | Abbkine |
| Molecular Weight: | 20.6 kDa |
| Type: | Interleukins |
| Alias: | BSF2; HGF; HSF; IFNB2; IL-6; Interleukin-6; Interleukin-6; IL-6 |
| Shipping Condition: | RT |
| Unit(s): | 1 mg, 100 ug, 20 ug, 5 ug |
Description
Description: Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
Additional Text
Gene Name
IL6
Gene ID
3569
Uniprot ID
P05231
Short Description
Human IL-6 protein, expressed in E. coli
PRP1012 Datasheet
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