Human TNF-α protein
Catalogue Number: PRP1013-ABK
| Manufacturer: | Abbkine |
| Molecular Weight: | 17.7 kDa |
| Type: | Cytokines |
| Alias: | DIF; TNF-α; TNFA; TNFSF2; Tumor necrosis factor; TNF |
| Shipping Condition: | RT |
| Unit(s): | 1 mg, 10 ug, 100 ug, 50 ug |
Description
Description: Tumor necrosis factor α (TNF-α), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-α. TNF-α protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-α is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
Additional Text
Gene Name
TNF
Gene ID
7124
Uniprot ID
P01375
Short Description
Human TNF-α protein, expressed in E. coli
PRP1013 Datasheet
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