Human TNF-alpha protein

Catalogue Number: PRP1013-ABK

Manufacturer:Abbkine
Molecular Weight:17.7 kDa
Type:Cytokines
Alias:DIF; TNF-alpha; TNFA; TNFSF2; Tumor necrosis factor; TNF
Shipping Condition:RT
Unit(s): 1 mg, 10 ug, 100 ug, 50 ug

Description

Description: Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.

Additional Text

Gene Name

TNF

Gene ID

7124

Uniprot ID

P01375

Short Description

Recombinant Human TNF-alpha Protein (Tumor necrosis factor) expressed in E. coli.

Price
922.00


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