Mouse IFN-gamma protein, His Tag

Catalogue Number: PRP1015-ABK

Manufacturer:Abbkine
Molecular Weight:16.9 kDa
Type:Cytokines
Alias:IFG; IFI; IFN gamma; Interferon Gamma; Interferon gamma; IFNG
Shipping Condition:RT
Unit(s): 1 mg, 100 ug, 20 ug, 500 ug

Description

Description: IFN gamma, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.

Additional Text

Gene Name

IFNG

Uniprot ID

P01580

Gene ID

15978

Short Description

Recombinant Mouse IFN-gamma Protein (Interferon gamma) expressed in E. coli.

Price
922.00


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