Human CD38 protein, His tag (Animal-Free)
Catalogue Number: PRP2027-ABK
| Manufacturer: | Abbkine |
| Molecular Weight: | 31 KD |
| Type: | Other Enzymes |
| Alias: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1 |
| Shipping Condition: | RT |
| Unit(s): | 1 mg, 10 ug, 100 ug, 50 ug |
Description
Description: CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose .CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells . Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic β cells.
Additional Text
Gene ID
952
Gene Name
CD38
Uniprot ID
P28907
Short Description
Human CD38 protein, His tag (Animal-Free), expressed in HEK293 Cells
PRP2027 Datasheet
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