Human PTP alpha/PTPRA Protein (PTP-HB10A)
Catalogue Number: PTP-HB10A-KAT
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 73.00 kDa. The protein migrates to 68-75 kDa based on Bis-Tris PAGE result. |
| Physical state: | Liquid |
| Type: | Other Recombinant Protein |
| Alias: | R-PTP-alpha; PTPRA; PTPA; PTPRL2; PTP alpha; HEPTP; HLPR; HPTPA |
| Host Cell: | Baculovirus-Insect Cells(Sf9) |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
| Application: | WB |
Description
Description: The receptor protein-tyrosine phosphatase α (encoded by PTPRA), a 130-kDa transmembrane PTP, has shown to be a physiological regulator for PTK c-Src and the kinases involved in integrin signaling pathway including FAK and P130cas. The activation of PTPRA on Src Y530 dephosphorylation led to cellular transformation, which suggested that PTPRA might be an oncogenic gene.
Additional Text
Protein Tag
HIS Tag
Storage Note
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin
Less than 1 EU per µg by the LAL method.
Short Description
Recombinant Human PTP alpha/PTPRA Protein is expressed from Baculovirus-Insect Cells(Sf9) with His tag at the C-terminus.It contains Ala183-Lys802.
PTP-HB10A Datasheet
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